noun · 5 senses · updated from the 2026-07-25 local source snapshot
Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.
Sound
Pronunciation
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/ænˈtæɡənɪzəm/
Southern-England:Recorded audio is listed in the source snapshot.
CMU ARPABET:AE0 N T AE1 G AH0 N IH2 Z AH0 M
Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.
1
noun
Meaning 1
A strong natural dislike or hatred; antipathy.
Definition source: English Wiktionary via Wiktextract
Usage: countable, uncountable
Examples
Their longstanding antagonism is manifested in frequent scuffles and shouting matches.
Meaning relationships
Synonyms: none provided
Antonyms: none provided
2
noun
Meaning 2
(biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure
Definition source: Princeton WordNet 3.0
No example sentence was provided for this meaning.
an actively expressed feeling of dislike and hostility
Definition source: Princeton WordNet 3.0
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: none provided
Antonyms: none provided
Broader terms: dislike, hostility, enmity, ill will
4
noun
Meaning 4
the relation between opposing principles or forces or factors
Definition source: Princeton WordNet 3.0
Examples
the inherent antagonism of capitalism and socialism
Meaning relationships
Synonyms: none provided
Antonyms: none provided
Broader terms: opposition, oppositeness
5
noun
Meaning 5
a state of deep-seated ill-will
Definition source: Princeton WordNet 3.0
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: hostility, enmity
Antonyms: none provided
Broader terms: state
Narrower terms: latent hostility, tension, war, state of war, cold war, suspicion
History
Etymology
From Ancient Greek ἀνταγωνιστής (antagōnistḗs, “opponent”), from ἀνταγωνίζομαι (antagōnízomai, “antagonize”), from ἀγών (agṓn, “contest”) (English agon).
Across languages
Translations
30 source translations are retained for this English entry.