Standard Lemma guide

carbamidomethylation

noun · 1 senses · updated from the 2026-07-25 local source snapshot

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1

noun

Meaning 1

A chemical modification where a carbamidomethyl group is added to cysteine residues in proteins, usually using iodoacetamide, to block reactive thiol groups and prevent disulfide bonds from reforming, especially during mass spectrometry sample preparation.

Definition source: English Wiktionary via Wiktextract

Topics: chemistry, natural-sciences, organic-chemistry, physical-sciences

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Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

From carbamidomethyl + -ation.