Standard Lemma guide

clozapine

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ˈkləʊ.zə.piːn/
  • General-American: /ˈkloʊ.zəˌpin/
  • CMU ARPABET: K L OW1 Z AH0 P AY2 N Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.

1

noun

Meaning 1

A sedative drug used to treat schizophrenia.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: Clozaril

Antonyms: none provided

Broader terms: major tranquilizer, major tranquillizer, major tranquilliser, antipsychotic drug, antipsychotic agent, antipsychotic, neuroleptic drug, neuroleptic agent, neuroleptic

History

Etymology

Etymology tree Proto-Indo-European *ǵhelh3- Proto-Hellenic *khlōrós Ancient Greek χλωρός (khlōrós) English chlo(ro)- Arabic لُبَان (lubān) Proto-Indo-European *yew- Proto-Indo-European *-os Proto-Indo-European *yéwos Proto-Indo-Iranian *yáwas Sanskrit यव (yava)bor.? Proto-Austronesian *zawa Proto-Malayo-Polynesian *zawader.? Old Javanese jawa Old Javanese -i Old Javanese Jawi Javanese ꦗꦮꦶ (jawi)der. Arabic جَاوَة (jāwa) Proto-Afroasiatic Proto-Semitic Arabic ـِيّ (-iyy) Arabic جَاوِيّ (jāwiyy) Arabic لُبَان جَاوِيّ (lubān jāwiyy)bor. Catalan benjuíder. Middle French benjoinder. English benzoin English benzo- Proto-Indo-European *dwóh1 Proto-Indo-European *dwi- Proto-Hellenic *dwi- Ancient Greek δῐ- (dĭ-)bor. Latin di-bor. English di- Proto-Indo-European *né Proto-Indo-European *n̥- Proto-Hellenic *ə- Ancient Greek ᾰ̓- (ă-) Proto-Indo-European *gweyh3- Proto-Indo-European *-wós Proto-Indo-European *gwih3wós Proto-Indo-European *gwíh3weti Proto-Hellenic *gwyṓw-ō Proto-Hellenic *ďṓwō Ancient Greek ζώω (zṓō) Ancient Greek ζῶ (zô) Proto-Indo-European *-h2 Proto-Indo-European *-éh2 Ancient Greek -ᾱ (-ā) Ancient Greek -η (-ē) Ancient Greek ζωή (zōḗ) French azotebor. English azote English az- Proto-Afroasiatic *sṗɣ? Proto-Semitic *šabʕ-bor.? Proto-Indo-European *septḿ̥ Proto-Hellenic *heptə́ Ancient Greek ἑπτᾰ́ (heptắ)der. French hepta- Proto-Indo-European *-nós Proto-Indo-European *-iHnos Proto-Italic *-īnos Latin -īnus French -in Proto-Indo-European *-h2 Proto-Indo-European *-eh2 Proto-Italic *-ā Latin -am Old French -e French -e French -ine English -epine English azepine English diazepine English -zapine English clozapine From chlo(ro)- + -zapine (“alteration of (benzodi)azepine”).