Standard Lemma guide

cofactor

noun · 6 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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No pronunciation record was provided for this word.

1

noun

Meaning 1

A contributing factor.

Definition source: English Wiktionary via Wiktextract

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

A substance, especially a coenzyme or a metal, that must be present for an enzyme to function.

Definition source: English Wiktionary via Wiktextract

Topics: biochemistry, biology, chemistry, microbiology, natural-sciences, physical-sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

3

noun

Meaning 3

A molecule that binds to and regulates the activity of a protein.

Definition source: English Wiktionary via Wiktextract

Topics: biochemistry, biology, chemistry, microbiology, natural-sciences, physical-sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

4

noun

Meaning 4

The result of a number being divided by one of its factors.

Definition source: English Wiktionary via Wiktextract

Topics: mathematics, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

5

noun

Meaning 5

The signed determinant of the submatrix produced by removing the row and column containing a specified element; primarily used in the recursive definition and calculation of the determinant of a matrix.

Definition source: English Wiktionary via Wiktextract

Topics: linear-algebra, mathematics, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

6

noun

Meaning 6

a substance (as a coenzyme) that must join with another to produce a given result

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

Broader terms: compound, chemical compound

History

Etymology

Etymology tree Proto-Indo-European *ḱe? Proto-Indo-European *ḱóm Proto-Italic *kom Proto-Italic *kom- Latin con- Latin co-der. English co- English factor English cofactor From co- + factor.

Across languages

Translations

8 source translations are retained for this English entry.

  • Chinese Mandarin: 輔因子 /辅因子 (fǔyīnzǐ) — substance that must be present for an enzyme to function
  • Finnish: kofaktori — substance that must be present for an enzyme to function
  • Hungarian: kofaktor — substance that must be present for an enzyme to function
  • Japanese: 補因子 (hoinshi) — substance that must be present for an enzyme to function
  • Kazakh: кофактор (kofaktor) — substance that must be present for an enzyme to function
  • Spanish: cofactor — substance that must be present for an enzyme to function
  • Tagalog: kakabuo — substance that must be present for an enzyme to function
  • Turkish: kofaktör — substance that must be present for an enzyme to function