Standard Lemma guide

dedifferentiation

noun · 3 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • UK: /diːˌdɪfəɹɛnʃɪˈeɪʃən/

1

noun

Meaning 1

The loss or reversal of differentiation.

Definition source: English Wiktionary via Wiktextract

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

The biological process whereby cells revert from a specialized function to a simpler or less specialized form.

Definition source: English Wiktionary via Wiktextract

Topics: biology, natural-sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

3

noun

Meaning 3

the loss of specialization in form or function

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

Broader terms: adaptation, adaption, adjustment

History

Etymology

Etymology tree Proto-Indo-European *de Proto-Indo-European *-h1 Proto-Indo-European *déh1 Proto-Italic *dē Latin dē Latin dē-der. English de- Proto-Indo-European *dwóh1 Proto-Indo-European *d(w)is- Proto-Italic *dis- Latin dis- Proto-Indo-European *bher- Proto-Indo-European *bhéreti Proto-Italic *ferō Latin ferō Latin differō Latin differēns Proto-Indo-European *-(i)yós Proto-Italic *-ijos Proto-Italic *-ios Old Latin -ios Latin -ius Latin -ia Latin differentia New Latin differentiō New Latin differentiātusbor. English differentiate Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English -ion English differentiation English dedifferentiation From de- + differentiation.

Across languages

Translations

3 source translations are retained for this English entry.

  • Greek: αποδιαφοροποίηση (apodiaforopoíisi) — loss or reversal of differentiation
  • Italian: dedifferenziazione — loss or reversal of differentiation
  • Italian: sdifferenziamento — loss or reversal of differentiation