Standard Lemma guide

denosumab

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /dɪˈnɒs.jʊ.mab/
  • General-American: /dɛnˈoʊ.səˌmæb/
  • General-American: /dəˈnɑs.jəˌmæb/

1

noun

Meaning 1

A drug (trademarks Prolia and Xgera) that is a genetically engineered monoclonal antibody that reduces bone resorption and increases bone mass by inhibiting osteoclast formation and function and that is administered by injection to prevent fractures associated with osteoporosis and malignant tumors of bone and to treat hypercalcemia associated with various cancers.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

From arbitrary prefix den- + -os- (“bone”) + -umab (“human monoclonal antibody”).