Standard Lemma guide

doxepin

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ˈdɒk.səp.ɪn/
  • General-American: /ˈdɑk.səp.ɪn/

1

noun

Meaning 1

A psychotropic agent with tricyclic antidepressant and anxiolytic properties.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: doxepin hydrochloride, Adapin, Sinequan

Antonyms: none provided

Broader terms: tricyclic, tricyclic antidepressant, tricyclic antidepressant drug

History

Etymology

From [Term?] + -oxepin (“tricyclic compound”).