noun · 3 senses · updated from the 2026-07-25 local source snapshot
Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.
Sound
Pronunciation
Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.
Southern-England:Recorded audio is listed in the source snapshot.
Australian:/ˈef.ɪ.kə.si/
Australian:[ˈef.ɪ.kə.sɪi]cultivated
New-Zealand:/ˈef.ə.kə.si/
CMU ARPABET:EH1 F IH0 K AE2 S IY0
Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.
1
noun
Meaning 1
The ability to produce a desired effect under ideal testing conditions.
Definition source: English Wiktionary via Wiktextract
Usage: uncountable, usually
Examples
2005, Flay et al. Standards of Evidence: Criteria for Efficacy, Effectiveness and Dissemination DOI: 10.1007/s11121-005-5553-y Efficacy refers to the beneficial effects of a program or policy under optimal conditions of delivery, whereas effectiveness refers to effects of a program or policy under more real-world conditions.
Meaning relationships
Synonyms: none provided
Antonyms: none provided
2
noun
Meaning 2
A degree of ability to produce a desired effect; effectiveness.
Definition source: English Wiktionary via Wiktextract
Usage: uncountable, usually
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: none provided
Antonyms: none provided
3
noun
Meaning 3
capacity or power to produce a desired effect
Definition source: Princeton WordNet 3.0
Examples
concern about the safety and efficacy of the vaccine