Standard Lemma guide

estradiol

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • General-American: /ˌɛs.tɹəˈdaɪˌɔl/
  • General-American:
  • US: Recorded audio is listed in the source snapshot.

1

noun

Meaning 1

A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C18H24O2) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer.

Definition source: English Wiktionary via Wiktextract

Usage: US, countable, uncountable

Topics: biochemistry, biology, chemistry, microbiology, natural-sciences, physical-sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: oestradiol

Antonyms: none provided

Broader terms: estrogen, oestrogen

History

Etymology

Internationalism. From estratriene (“estra(triene)”) + diol. By surface analysis, estra- + di- + -ol.

Across languages

Translations

15 source translations are retained for this English entry.

  • Chinese Mandarin: 雌二醇 (cí'èrchún) — Translations
  • Czech: estradiol — Translations
  • Finnish: estradioli — Translations
  • French: oestradiol — Translations
  • French: estradiol — Translations
  • German: Östradiol — Translations
  • Italian: estradiolo — Translations
  • Japanese: エストラジオール (esutorajiōru) — Translations
  • Polish: estradiol — Translations
  • Portuguese: estradiol — Translations
  • Russian: эстрадио́л (estradiól) — Translations
  • Serbo-Croatian: estradiol — Translations
  • Slovak: estradiol — Translations
  • Slovene: estradiol — Translations
  • Swedish: östradiol — Translations