Standard Lemma guide

estrone

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • General-American: /ˈɛˌstɹoʊn/
  • General-American: Recorded audio is listed in the source snapshot.

1

noun

Meaning 1

A natural estrogenic hormone that is a ketone C18H22O2 found in the body chiefly as a metabolite of and less potent than estradiol, that is also secreted especially by the ovaries, and that is used to treat various conditions (such as ovarian failure and menopausal symptoms) relating to estrogen deficiency.

Definition source: English Wiktionary via Wiktextract

Usage: US, countable, uncountable

Qualifier: steroids

Topics: biochemistry, biology, chemistry, medicine, microbiology, natural-sciences, pharmacology, physical-sciences, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: oestrone, theelin, Estronol

Antonyms: none provided

Broader terms: estrogen, oestrogen, ketosteroid

History

Etymology

Etymology tree Proto-Indo-European *h1eysh2-der. Ancient Greek οἶστρος (oîstros)der. Latin oestrusbor. English estrus Ancient Greek -ο- (-o-)der. Latin -o-bor. English -o- English estro- English estr- German Ketonbor. English ketone English -one English estrone From estr- + -one.