Phrase guide

fibrodysplasia ossificans progressiva

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • Received-Pronunciation: /ˌfaɪbɹəʊdɪsˈpleɪzɪə ɒˈsɪfɪkɑːnz pɹəˈɡɹɛsɪvə/
  • Received-Pronunciation: /-ˈpleɪʒə-/
  • General-American: /ˌfaɪbɹoʊdɪsˈpleɪʒ(i)ə ɒˈsɪfɪkænz pɹəˈɡɹɛsɪvə/
  • General-American: /-ˈpleɪziə-/
  • General-American: /-pɹoʊ-/
  • General-American: Recorded audio is listed in the source snapshot.

1

noun

Meaning 1

A very rare, disabling genetic disorder of the connective tissue in which fibrous tissue (including ligaments, muscles, and tendons) ossifies (“transforms into bone”) when damaged.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Qualifier: medical genetics

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: FOP, Münchmeyer disease, myositis ossificans progressiva, stone man syndrome

Antonyms: none provided

History

Etymology

PIE word *h3ésth1 From English fibrodysplasia, and borrowed from New Latin ossificans + Latin prōgressīvā, literally “abnormal development of fibrous tissue with ossification that is progressive”: * Fibrodysplasia is derived from fibro- (prefix meaning ‘fibre; fibrous’) (from Latin fibra (“fibre; filament”), ultimately from Proto-Indo-European *bheyd- (“to split”)) + dysplasia (“abnormal development of cells or tissue”) (from dys- (prefix meaning ‘abnormal; disease’) + -plasia (suffix meaning ‘formation; growth’)). * Ossificans is from Latin ossīs (a plural form of ossum (“bone”), ultimately from Proto-Indo-European *h3ésth1 (“bone”)) + -ficāns (the present active participle of -ficō (suffix forming chiefly causative or factitive verbs)). * Prōgressīvā is the ablative feminine singular of prōgressīvus (“progressive”), from prōgressus (“advanced, proceeded; developed, progressed”) (the perfect active participle of prōgredior (“to advance, proceed; (figurative) to develop, progress”), from prō- (prefix denoting a forward direction) + gradior (“to step; to walk; to advance”) (ultimately from Proto-Indo-European *ghredh- (“to go; to walk”))) + -īvus (suffix forming adjectives). The disease was originally termed myositis ossificans progressiva in 1868. The use of fibrodysplasia in place of myositis was suggested by K. H. Bauer and W. Bode in 1940, and adopted by the American medical geneticist Victor A. McKusick (1921–2008) in his work Heritable Disorders of Connective Tissue (1956).

Across languages

Translations

25 source translations are retained for this English entry.

  • Arabic: خلل التنسج الليفي المعظم المترقي — genetic disorder in which fibrous tissue ossifies when damaged
  • Basque: fibrodisplasia osifikatzaile progresibo — genetic disorder in which fibrous tissue ossifies when damaged
  • Catalan: fibrodisplàsia ossificant progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Chinese Mandarin: 進行性骨化性纖維發育不良 /进行性骨化性纤维发育不良 (jìnxíngxìnggǔhuàxìngxiānwéifāyùbùliáng) — genetic disorder in which fibrous tissue ossifies when damaged
  • Czech: fibrodysplasia ossificans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Dutch: fibrodysplasia ossificans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Esperanto: progresa ostiĝa fibrodisplazio — genetic disorder in which fibrous tissue ossifies when damaged
  • Finnish: fibrodysplasia ossificans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • German: Fibrodysplasia ossificans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Hebrew: תסמונת FOP — genetic disorder in which fibrous tissue ossifies when damaged
  • Italian: fibrodisplasia ossificante progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Japanese: 進行性骨化性線維異形成症 (shin kōsei kotsu ka sei sen ī kei seishou) — genetic disorder in which fibrous tissue ossifies when damaged
  • Korean: 진행성 골화성 섬유이형성증 (jinhaengseong golhwaseong seomyuihyeongseongjeung) — genetic disorder in which fibrous tissue ossifies when damaged
  • Latvian: progresējošā osificējošā fibrodisplāzija — genetic disorder in which fibrous tissue ossifies when damaged
  • Limburgish: fibrodysplasia ossificans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Macedonian: прогресивна осифирачка фибродисплазија (progresivna osifiračka fibrodisplazija) — genetic disorder in which fibrous tissue ossifies when damaged
  • Malayalam: ഫൈബ്രോഡിസ്പ്ലാസിയ ഓസിഫിക്കൻസ് പ്രോഗ്രെസ്സിവ (phaibrōḍisplāsiya ōsiphikkaṉsŭ prōgressiva) — genetic disorder in which fibrous tissue ossifies when damaged
  • Persian: فیبرودیسپلازی استخوانیشونده پیشرونده — genetic disorder in which fibrous tissue ossifies when damaged
  • Polish: postępujące kostniejące zapalenie mięśni — genetic disorder in which fibrous tissue ossifies when damaged
  • Portuguese: fibrodisplasia ossificante progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Romanian: fibrodisplazie osificantă progresivă — genetic disorder in which fibrous tissue ossifies when damaged
  • Russian: фибродисплази́я оссифици́рующая прогресси́рующая (fibrodisplazíja ossificírujuščaja progressírujuščaja) — genetic disorder in which fibrous tissue ossifies when damaged
  • Spanish: fibrodisplasia osificante progresiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Turkish: fibrodisplazi ossifikans progressiva — genetic disorder in which fibrous tissue ossifies when damaged
  • Vietnamese: hội chứng người hoá đá — genetic disorder in which fibrous tissue ossifies when damaged