Standard Lemma guide

fluoxetine

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • Received-Pronunciation: /fluːˈɒk.sə.tiːn/
  • General-American: /fluːˈaksətiːn/

1

noun

Meaning 1

A synthetic compound which inhibits the uptake of serotonin in the brain and is taken to treat depression.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable, usually

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: fluoxetine hydrocholoride, Prozac, Sarafem

Antonyms: none provided

Broader terms: selective-serotonin reuptake inhibitor, SSRI

History

Etymology

Etymology tree Proto-Indo-European *bhel-der. Proto-Indo-European *bhlewH-der. Proto-Indo-European *bhluH-yé-ti? Latin fluō Proto-Indo-European *-os Proto-Indo-European *-s Proto-Indo-European *-ōs Proto-Italic *-ōs Latin -or Latin fluor Ancient Greek -ο- (-o-)der. Latin -o-bor. English -o- English flu(oro)- Proto-Indo-European *h2eḱ-der.? Ancient Greek ὀξῠ́ς (oxŭ́s)bor. English ox(y)- German Tolu German Toluinder. English t(oluene) Egyptian jmnbor. Ancient Greek Ᾰ̓́μμων (Ắmmōn)bor. Latin Ammōn Latin ammoniacusder. English ammonia Proto-Indo-European *-nós Proto-Indo-European *-iHnos Proto-Italic *-īnos Latin -īnusder. Old French -inbor. Middle English -in English -ine English (am)ine English fluoxetine From flu(oro)- + ox(y)- + t(oluene) + (am)ine.

Across languages

Translations

13 source translations are retained for this English entry.

  • Chinese Mandarin: 氟西汀 (fúxītīng) — SSRI antidepressant drug
  • Chinese Mandarin: 氟苯氧丙胺 (fúběnyǎngbǐng'àn) — SSRI antidepressant drug
  • Czech: fluoxetin — SSRI antidepressant drug
  • Esperanto: fluoksetino — SSRI antidepressant drug
  • Finnish: fluoksetiini — SSRI antidepressant drug
  • Italian: fluoxetina — SSRI antidepressant drug
  • Japanese: フルオキセチン (furuokisechin) — SSRI antidepressant drug
  • Korean: 플루옥세틴 (peulluoksetin) — SSRI antidepressant drug
  • Latin: fluoxetinum — SSRI antidepressant drug
  • Portuguese: fluoxetina — SSRI antidepressant drug
  • Russian: флуоксети́н (fluoksetín) — SSRI antidepressant drug
  • Spanish: fluoxetina — SSRI antidepressant drug
  • Turkish: fluoksetin — SSRI antidepressant drug