Phrase guide

frameshift mutation

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

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1

noun

Meaning 1

A genetic mutation that either inserts or deletes a number of nucleotides that is not divisible by three (i.e., a non-integer number of codons), altering the reading frame of the portion of the gene downstream of the mutation and causing it to code for a completely different protein sequence.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: biology, genetics, medicine, natural-sciences, sciences

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Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

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