Standard Lemma guide

haploinsufficiency

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

No pronunciation record was provided for this word.

1

noun

Meaning 1

The state of a diploid organism having only a single copy of a particular gene, the other copy being inactivated due to mutation

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: biology, genetics, medicine, natural-sciences, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

Etymology tree Proto-Indo-European *sem- Proto-Indo-European *sm̥- Proto-Hellenic *hə- Ancient Greek ᾰ̔- (hă-) Ancient Greek -πλόος (-plóos) Ancient Greek ᾰ̔πλόος (hăplóos)der. English haplo- English insufficiency English haploinsufficiency From haplo- + insufficiency.

Across languages

Translations

1 source translations are retained for this English entry.

  • Finnish: haploinsuffisienssi — Translations