Phrase guide

Hirschsprung's disease

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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1

noun

Meaning 1

Congenital aganglionic megacolon, a disorder in which the bowel is obstructed by an aganglionic section of bowel and the colon becomes enlarged.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

congenital condition in which the colon does not have the normal network of nerves; there is little urge to defecate so the feces accumulate and cause megacolon

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: congenital megacolon

Antonyms: none provided

Broader terms: genetic disease, genetic disorder, genetic abnormality, genetic defect, congenital disease, inherited disease, inherited disorder, hereditary disease, hereditary condition

History

Etymology

After Harald Hirschsprung (1830–1916), Danish physician who first described it.

Across languages

Translations

5 source translations are retained for this English entry.

  • Chinese Mandarin: 先天性巨結腸症 /先天性巨结肠症 (xiāntiānxìng jùjiécháng zhèng) — congenital aganglionic megacolon
  • Chinese Mandarin: 赫希施普龍氏病 /赫希施普龙氏病 (Hèxīshīpǔlóngshìbìng) — congenital aganglionic megacolon
  • Finnish: Hirschsprungin tauti — congenital aganglionic megacolon
  • French: maladie de Hirschsprung — congenital aganglionic megacolon
  • Russian: боле́знь Ги́ршпрунга (boléznʹ Gíršprunga) — congenital aganglionic megacolon