noun · 2 senses · updated from the 2026-07-25 local source snapshot
Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.
Sound
Pronunciation
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/ɪˌmjuːnəʊdɪˈfɪʃənsi/
Southern-England:Recorded audio is listed in the source snapshot.
CMU ARPABET:IH2 M Y UW0 N OW0 D IH2 F IH1 SH AH0 N S IY0
Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.
1
noun
Meaning 1
A depletion in the body's natural immune system, or in some component of it.
Definition source: English Wiktionary via Wiktextract
Usage: countable, uncountable
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: immunocompromise, immunosuppression
Antonyms: immunocompetence, immunocompetency
2
noun
Meaning 2
immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
Definition source: Princeton WordNet 3.0
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: none provided
Antonyms: immunocompetence
Broader terms: immunological disorder
Narrower terms: AIDS, acquired immune deficiency syndrome, agammaglobulinemia, hypogammaglobulinemia, severe combined immunodeficiency, severe combined immunodeficiency disease, SCID
History
Etymology
Etymology tree Proto-Indo-European *mey- Proto-Indo-European *moy-nósder. Proto-Italic *moinos Latin mūnus Proto-Indo-European *né Proto-Indo-European *n̥- Proto-Italic *n̥- Latin in- Proto-Indo-European *-is Proto-Indo-European *-h2 Proto-Indo-European *-ih2der.? Proto-Italic *-is Latin -is Latin in- -is Latin immūnisder. Middle French immunbor. Middle English English immune Ancient Greek -ο- (-o-)der. Latin -o-bor. English -o- English immuno- English deficiency English immunodeficiency From immuno- + deficiency.
Across languages
Translations
24 source translations are retained for this English entry.
Basque:
immunoeskasia
— A depletion in the body's natural immune system
Belarusian:
імунадэфіцы́т
(imunadeficýt)
— A depletion in the body's natural immune system
Catalan:
immunodeficiència
— A depletion in the body's natural immune system
Chinese Mandarin:
免疫缺陷
(miǎnyì quēxiàn)
— A depletion in the body's natural immune system
Danish:
immundefekt
— A depletion in the body's natural immune system
Dutch:
immuundeficiëntie
— A depletion in the body's natural immune system
Finnish:
immuunivaje
— A depletion in the body's natural immune system
Finnish:
immuunipuutos
— A depletion in the body's natural immune system
French:
immunodéficience
— A depletion in the body's natural immune system
German:
Immundefekt
— A depletion in the body's natural immune system
Hungarian:
immunhiány
— A depletion in the body's natural immune system
Italian:
immunodeficienza
— A depletion in the body's natural immune system
Polish:
upośledzenie odporności
— A depletion in the body's natural immune system
Polish:
niedobór odporności
— A depletion in the body's natural immune system
Portuguese:
imunodeficiência
— A depletion in the body's natural immune system
Romanian:
imunodeficiență
— A depletion in the body's natural immune system
Russian:
иммунодефици́т
(immunodeficít)
— A depletion in the body's natural immune system
Slovak:
imunodeficiencia
— A depletion in the body's natural immune system
Spanish:
inmunodeficiencia
— A depletion in the body's natural immune system
Swedish:
immunbrist
— A depletion in the body's natural immune system
Swedish:
immundefekt
— A depletion in the body's natural immune system
Swedish:
immunsvaghet
— A depletion in the body's natural immune system
Thai:
ภูมิคุ้มกันบกพร่อง
(puum-kúm-gan-bòk-prɔ̂ng)
— A depletion in the body's natural immune system
Ukrainian:
імунодефіци́т
(imunodeficýt)
— A depletion in the body's natural immune system