Standard Lemma guide

isotretinoin

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ˌʌɪ.sə(ʊ).tɹəˈtɪn.əʊ.ɪn/
  • General-American: /ˌaɪ.soʊˈtɹɛt.ɪˌnoʊ.ɪn/

1

noun

Meaning 1

A cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: chemistry, medicine, natural-sciences, organic-chemistry, pharmacology, physical-sciences, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: Accutane

Antonyms: none provided

History

Etymology

From iso- + tretinoin.