Standard Lemma guide

loperamide

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ləʊˈpɛ.ɹə.mʌɪd/
  • General-American: /loʊˈpɛɹ.əˌmaɪd/

1

noun

Meaning 1

A synthetic antidiarrheal agent of the opiate class (trademark Imodium) that slows intestinal peristalsis and is taken orally in the form of its hydrochloride C29H33ClN2O2·HCl to control acute nonspecific diarrhea or chronic diarrhea associated with inflammatory bowel disease or to reduce fecal volume discharged from ileostomies.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

Etymology tree Proto-Indo-European *ǵhelh3- Proto-Hellenic *khlōrós Ancient Greek χλωρός (khlōrós) English (ch)lo(ro)- Indo-Aryanbor. Ancient Greek πέπερῐ (péperĭ)bor. Latin piper English -idine English (pi)per(idine) English -amide English loperamide From (ch)lo(ro)- + (pi)per(idine) + -amide.