Phrase guide

Lou Gehrig's disease

noun · 3 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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1

noun

Meaning 1

Synonym of amyotrophic lateral sclerosis.

Definition source: English Wiktionary via Wiktextract

Usage: US, uncountable

Topics: medicine, pathology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: amyotrophic lateral sclerosis

Antonyms: none provided

2

noun

Meaning 2

Alternative form of Lou Gehrig's disease.

Definition source: English Wiktionary via Wiktextract

Usage: alt-of, alternative, uncountable

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

3

noun

Meaning 3

thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: amyotrophic lateral sclerosis, ALS

Antonyms: none provided

Broader terms: nervous disorder, neurological disorder, neurological disease, sclerosis, induration

History

Etymology

Named after New York Yankees baseball player Lou Gehrig (1903–1941), a prominent sufferer of the disease. The disease was known before Gehrig suffered it, but his fame led to his name being associated with it.