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A person of influence, especially a politician, who is being manipulated by an enemy power to harm the interests of their own country, possibly without their own full awareness.
Definition source: English Wiktionary via Wiktextract
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From the title of the 1959 novel or 1962 film The Manchurian Candidate, in which the son of a prominent US political family is brainwashed into being an unwitting assassin for a communist conspiracy. First known generic use in 1970.