Phrase guide

Meckel-Gruber syndrome

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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1

noun

Meaning 1

A rare, lethal ciliopathic genetic disorder characterized by renal cystic dysplasia, central nervous system malformations (occipital encephalocele), polydactyly (postaxial), hepatic developmental defects, and pulmonary hypoplasia due to oligohydramnios.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: dysencephalia splanchnocystica, Meckel syndrome

Antonyms: none provided

History

Etymology

Named after Johann Meckel and Georg Gruber.