Standard Lemma guide

mefloquine

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ˈmɛf.lə.kwiːn/
  • Received-Pronunciation: /ˈmɛf.lək.wɪn/
  • General-American: /ˈmɛf.lək.wɪn/
  • General-American: Recorded audio is listed in the source snapshot.

1

noun

Meaning 1

An antimalarial drug C17H16F6N2O similar to quinine that consists of a fluorinated derivative of quinoline and is used in the form of its hydrochloride for the prevention and treatment of malaria.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: Lariam

Antonyms: none provided

2

noun

Meaning 2

an antimalarial drug (trade name Larium and Mephaquine) that is effective in cases that do not respond to chloroquine; said to produce harmful neuropsychiatric effects on some people

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: mefloquine hydrochloride, Larium, Mephaquine

Antonyms: none provided

Broader terms: antimalarial, antimalarial drug

History

Etymology

Etymology tree Proto-Indo-European *médhu Proto-Hellenic *méthu Ancient Greek μέθυ (méthu) Proto-Indo-European *swel-der.? Ancient Greek ῡ̔́λη (hū́lē)der. German -yl German Methylbor. English me(thyl) Proto-Indo-European *bhel-der. Proto-Indo-European *bhlewH-der. Proto-Indo-European *bhluH-yé-ti? Latin fluō Proto-Indo-European *-os Proto-Indo-European *-s Proto-Indo-European *-ōs Proto-Italic *-ōs Latin -or Latin fluor Ancient Greek -ο- (-o-)der. Latin -o-bor. English -o- English fl(uor)o- English -quine English mefloquine From me(thyl) (“quinoline derivative”) + fl(uor)o- + -quine.