Standard Lemma guide

mercaptopurine

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /mɜːˌkap.tə(ʊ)ˈp(j)ʊə.ɹiːn/
  • Received-Pronunciation: /mɜːˌkap.tə(ʊ)ˈpjɔː.ɹiːn/
  • General-American: /mɚˌkæp.təˈpjʊɹˌin/

1

noun

Meaning 1

An thiol antimetabolite C5H4N4S that interferes especially with the metabolism of purine bases and the biosynthesis of nucleic acids and that is sometimes used in the treatment of acute leukemia.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: Purinethol

Antonyms: none provided

Broader terms: antimetabolite, immunosuppressant, immunosuppressor, immunosuppressive drug, immunosuppressive, immune suppressant drug

History

Etymology

Etymology tree Latin Mercurius Latin mercurium substratebor.? Proto-Indo-European *kap- Proto-Indo-European *-yéti Proto-Indo-European *kapyéti Proto-Italic *kapjō Old Latin kapiō Latin capiō Proto-Indo-European *-tós Proto-Italic *-tos Latin -tus Proto-Indo-European *-h2 Proto-Indo-European *-éh2 Proto-Indo-European *-yéti Proto-Indo-European *-eh2yéti Proto-Indo-European *-h2tiinflu. Proto-Italic *-ājō Proto-Italic *-āō Latin -ō Latin -tō Latin captō Latin captāns Latin mercurium captānsder. English mercapto- German Purinbor. English purine English mercaptopurine From mercapto- + purine.