Standard Lemma guide

metastasize

verb · 5 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • Received-Pronunciation: /mɪˈtæstəsaɪz/
  • Southern-England: Recorded audio is listed in the source snapshot.
  • General-American: /məˈtæstəˌsaɪz/
  • CMU ARPABET: M AH0 T AE1 S T AH0 S AY2 Z Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.

1

verb

Meaning 1

Of a disease (especially cancer) or a tumour: to form a metastasis (“a secondary focus away from the primary site”) in (a body organ).

Definition source: English Wiktionary via Wiktextract

Usage: British, English, Oxford, US, specifically, transitive

Topics: medicine, oncology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

verb

Meaning 2

To disseminate or spread (something, often an undesirable thing), especially in a destructive manner.

Definition source: English Wiktionary via Wiktextract

Usage: British, English, Oxford, US, figuratively, transitive

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

3

verb

Meaning 3

Of a disease (especially cancer) or a tumour: to undergo metastasis (“spreading from a primary site to one or more other sites in the body”).

Definition source: English Wiktionary via Wiktextract

Usage: British, English, Oxford, US, intransitive, specifically

Topics: medicine, oncology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

4

verb

Meaning 4

Of a thing, often one which is undesirable: to disseminate or spread, especially in a destructive manner.

Definition source: English Wiktionary via Wiktextract

Usage: British, English, Oxford, US, figuratively, intransitive

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

5

verb

Meaning 5

spread throughout the body

Definition source: Princeton WordNet 3.0

Examples

  • the cancer had metastasized and the patient could not be saved

Meaning relationships

Synonyms: metastasise

Antonyms: none provided

Broader terms: spread, distribute

History

Etymology

From metastasis + -ize (suffix forming verbs meaning to do things denoted by the adjectives or nouns the suffix is attached to). Metastasis is a learned borrowing from Late Latin metastasis (“(rhetoric) rapid or sudden transition from one argument, point, or topic to another”), and from its etymons Koine Greek μετάστασις (metástasis, “(rhetoric) rapid or sudden transition from one argument, point, or topic to another”) and Ancient Greek μετάστασις (metástasis, “change; removal; (medicine) movement of disease, pain, etc., from one part of the body to another”), from μετᾰ- (metă-, prefix denoting change in condition or position) (possibly ultimately from Proto-Indo-European *meth2) + στᾰ́σῐς (stắsĭs, “condition, state; position”) (ultimately from Proto-Indo-European *steh2- (“to stand (up)”)), modelled after μεθιστάναι (methistánai, “to change; to remove”). The use of French métastase (“metastasis”) to refer to the spread of cancer was coined in 1829 by the French gynecologist Joseph Récamier (1774–1852).

Across languages

Translations

27 source translations are retained for this English entry.

  • Catalan: metastatitzar — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Chinese Mandarin: 轉移 /转移 (zhuǎnyí) — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Danish: metastasere — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Dutch: metastaseren — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Dutch: uitzaaien — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Finnish: metastasoida — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Finnish: metastasoitua — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • French: métastaser — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • German: metastasieren — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • German: absiedeln — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Hungarian: metasztatizál — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Hungarian: áttétet képez — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Hungarian: áttétet ad — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Italian: metastatizzare — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Japanese: 転移する (ten'i suru) — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Macedonian: метастазира (metastazira) — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Polish: dawać przerzuty — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Polish: dać przerzuty — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Romanian: metastaza — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Spanish: metastatizar — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Spanish: metastizar — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Swedish: metastasera — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Vietnamese: di căn — (transitive) of a disease (especially cancer) or a tumour: to form a metastasis in (a body organ); (intransitive) to undergo metastasis
  • Finnish: levittää — (transitive) to disseminate or spread (something), especially in a destructive manner; (intransitive) to disseminate or spread, especially in a destructive manner — see also disseminate, spread
  • Finnish: levitä — (transitive) to disseminate or spread (something), especially in a destructive manner; (intransitive) to disseminate or spread, especially in a destructive manner — see also disseminate, spread
  • Polish: rozprzestrzeniać — (transitive) to disseminate or spread (something), especially in a destructive manner; (intransitive) to disseminate or spread, especially in a destructive manner — see also disseminate, spread
  • Polish: rozprzestrzenić — (transitive) to disseminate or spread (something), especially in a destructive manner; (intransitive) to disseminate or spread, especially in a destructive manner — see also disseminate, spread