Standard Lemma guide

metyrapone

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /mɪˈtɪ.ɹə.pəʊn/
  • Received-Pronunciation: /mɪˈtʌɪ.ɹə.pəʊn/
  • General-American: /məˈtɪɹ.əˌpoʊn/

1

noun

Meaning 1

A compound that inhibits the enzyme 17β-hydroxylase and prevents synthesis of glucocorticoids and mineralocorticoids by the adrenal gland, used chiefly for assessment of feedback control of the hypothalamic–pituitary axis in adrenal disease, and sometimes in the treatment of Cushing's syndrome and resistant edema; 2-methyl-1,2-di-3-pyridyl-1-propanone, C5H4N·CO·C(CH3)2·C5H4N.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

From meth- + (dip)yr(idyl) + -a- + (pro)p(an)one.