Standard Lemma guide

MPTP

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • US: Recorded audio is listed in the source snapshot.

1

noun

Meaning 1

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a byproduct of synthetic heroin, or MPPP, which causes parkinsonian symptoms in users; and a neurotoxin that degrades into MPP+ after crossing the blood-brain barrier, which causes a degradation of the dopaminergic neurons within the substantia nigra.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, neurology, neuroscience, neurotoxicology, sciences, toxicology

Examples

  • 2005 Dec 29, Petzinger, et al. Journal of Neuroscience Research http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16385585&query_hl=8&itool=pubmed_docsum The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

No etymology was provided for this word.