Phrase guide

nociplastic pain

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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1

noun

Meaning 1

Heightened responsiveness to sensory input, thought to result from dysfunction in the processing of pain signals by the central nervous system.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, sciences

Examples

  • 2019, Mark A. Jones, Darren A. Rivett, Clinical Reasoning in Musculoskeletal Practice, Elsevier, 2nd Edition, E-book Edition, page 40, Nociplastic pain is clearly dysfunctional as it serves no protective benefit to the people experiencing it. Nociplastic pain is significantly disproportionate to any plausible tissue contributions, persists beyond expected tissue healing times and may be recurrent in nature.
  • 2022, Deeba Minhas, Daniel J. Clauw, 88: Fibromyalgia and related syndromes, Marc C. Hochberg, Josef S. Smolen, Michael E. Weinblatt, Michael H. Weisman, Ellen M Gravallese, Desiree van der Heijde (editors), Rheumatology, Elsevier, 8th Edition, page 740, Fibromyalgia (FM) is the prototypical nociplastic pain syndrome.

Meaning relationships

Synonyms: central sensitisation

Antonyms: none provided

History

Etymology

No etymology was provided for this word.

Across languages

Translations

2 source translations are retained for this English entry.

  • German: noziplastischer Schmerz — pain thought to result from dysfunction in pain signal processing
  • German: Zentrale Sensitivierung — pain thought to result from dysfunction in pain signal processing