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To completely eliminate a dangerous or undesirable thing.
Definition source: English Wiktionary via Wiktextract
Usage: humorous, informal, often
No example sentence was provided for this meaning.
Meaning relationships
Synonyms: none provided
Antonyms: none provided
Alteration of dialog from the 1986 movie Aliens in which Ripley (Sigourney Weaver) proposes a solution to an infestation of dangerous creatures: "I say we take off and nuke the entire site from orbit. It's the only way to be sure."