Standard Lemma guide

-o-

interfix · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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No pronunciation record was provided for this word.

1

interfix

Meaning 1

A linking vowel inserted interconsonantally between two morphemes, to ease pronunciation, without contributing to the meaning. It frequently joins words or combining forms of Ancient Greek or Classical Latin origin in the classical compounds of New Latin and international scientific vocabulary, but it can also be used to join modern terms and even abbreviations, either formally or informally.

Definition source: English Wiktionary via Wiktextract

Usage: morpheme

Examples

  • extreme + -o- + -phile producing extremophile
  • blog + -o- + -sphere producing blogosphere
  • speed + -o- + meter producing speedometer
  • sadism + -o- + masochism producing sadomasochism
  • smell + -o- + vision producing smell-o-vision

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

interfix

Meaning 2

a monoclonal antibody derived from a murine source

Definition source: English Wiktionary via Wiktextract

Usage: morpheme

Topics: medicine, pharmacology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

Adopted from Latin -o-, originating ultimately from Ancient Greek -ο- (-o-). In English, the connective is found from the Middle English period in direct borrowings from Latin. Direct formations of English terms with the connective, always combining Greek or Latin roots, appear from the 16th or 17th century. From the 18th century, the suffix becomes productive in compounds where the second element is English. From about 1800, formations on all sorts of stems become common.

Designated in the USAN guidelines for non-proprietary names of monoclonal antibodies.

Across languages

Translations

6 source translations are retained for this English entry.

  • Irish: -a- — linking vowel between morphemes
  • Kashubian: -o- — linking vowel between morphemes
  • Polish: -o- — linking vowel between morphemes
  • Portuguese: -o- — linking vowel between morphemes
  • Portuguese: -ó- — linking vowel between morphemes
  • Portuguese: -ô- — linking vowel between morphemes