Standard Lemma guide

promethazine

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • Received-Pronunciation: /pɹəʊˈmɛ.θə.ziːn/
  • Received-Pronunciation: /pɹə-/
  • General-American: /pɹoʊˈmɛ.θəˌzin/
  • Southern-England: Recorded audio is listed in the source snapshot.
  • rhymes with -ɛθəziːn

1

noun

Meaning 1

A first-generation H1 receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, pharmacology, sciences

Examples

  • For quotations using this term, see Citations:promethazine.

Meaning relationships

Synonyms: Phenergan, pro

Antonyms: none provided

2

noun

Meaning 2

antihistamine (trade name Phenergan) used to treat allergies; also an antiemetic used to treat motion sickness

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: Phenergan

Antonyms: none provided

Broader terms: antiemetic, antiemetic drug, antihistamine

History

Etymology

From pro(p)- + meth- + (phenothi)azine.

Across languages

Translations

2 source translations are retained for this English entry.

  • Hungarian: prometazin — Translations
  • Spanish: prometazina — Translations