Standard Lemma guide

propositus

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

  • Received-Pronunciation: /prəʊˈpɒzɪtəs/
  • Received-Pronunciation: /prəˈpɒzɪtəs/
  • General-American: /proʊˈpɑzətəs/
  • General-American: /prəˈpɑzətəs/
  • General-American: [-ɾəs]

1

noun

Meaning 1

The first identified male case of an inherited disease in a family; the proband or index case.

Definition source: English Wiktionary via Wiktextract

Topics: biology, genetics, medicine, natural-sciences, sciences

Examples

  • The propositus was an elderly man who passed on the disorder to three of his four children and 9 of 14 grandchildren.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

the person immediately affected by or concerned with an action

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

Broader terms: person, individual, someone, somebody, mortal, soul

History

Etymology

Borrowed from Latin prōpositus.