Standard Lemma guide

scleroderma

noun · 3 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • CMU ARPABET: S K L IH2 R AH0 D ER1 M AH0 Digits mark lexical stress: 1 primary, 2 secondary, 0 unstressed.

1

noun

Meaning 1

A chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: medicine, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

genus of poisonous fungi having hard-skinned fruiting bodies: false truffles

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: genus Scleroderma

Antonyms: none provided

Broader terms: fungus genus

3

noun

Meaning 3

an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: dermatosclerosis

Antonyms: none provided

Broader terms: autoimmune disease, autoimmune disorder

Narrower terms: morphea

History

Etymology

From New Latin sclēroderma, from Ancient Greek σκληρός (sklērós, “hard”) + δέρμα (dérma, “skin, hide”). By surface analysis, sclero- + -derma.

Across languages

Translations

4 source translations are retained for this English entry.

  • Finnish: skleroderma — disease
  • Italian: sclerodermia — disease
  • Polish: twardzina — disease
  • Spanish: esclerodermia — disease