Phrase guide

severe combined immunodeficiency

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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No pronunciation record was provided for this word.

1

noun

Meaning 1

A genetic disorder characterized by the disturbed development of functional T cells and B cells, resulting in extreme vulnerability to infectious diseases.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: medicine, pathology, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: SCID, bubble boy disease, bubble boy syndrome, bubble baby disease, bubble baby syndrome

Antonyms: none provided

2

noun

Meaning 2

a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: severe combined immunodeficiency disease, SCID

Antonyms: none provided

Broader terms: immunodeficiency, monogenic disorder, monogenic disease

Narrower terms: ADA-SCID, X-linked SCID, X-SCID

History

Etymology

No etymology was provided for this word.