Phrase guide

sickle-cell disease

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

No pronunciation record was provided for this word.

1

noun

Meaning 1

A disease characterized by sickle-shaped red blood cells.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: drepanocytosis

Antonyms: none provided

Broader terms: hemoglobinopathy

2

noun

Meaning 2

a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: sickle-cell anemia, sickle-cell anaemia, crescent-cell anemia, crescent-cell anaemia, drepanocytic anemia, drepanocytic anaemia

Antonyms: none provided

Broader terms: monogenic disorder, monogenic disease, anemia, anaemia

History

Etymology

No etymology was provided for this word.