Phrase guide

substantia nigra

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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No pronunciation record was provided for this word.

1

noun

Meaning 1

A brain structure located in the mesencephalon (midbrain) that plays an important role in reward, addiction, and movement, damage to which occurs in Parkinson's and Parkinsonian patients.

Definition source: English Wiktionary via Wiktextract

Topics: anatomy, medicine, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a layer of deeply pigmented grey matter in the midbrain; associated with the striate body; is involved in metabolic disturbances associated with Parkinson's disease and with Huntington's disease

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: nucleus niger, locus niger

Antonyms: none provided

Broader terms: neural structure

History

Etymology

Scientific Latin, from substantia (“substance”) + nigra (“black”).

Across languages

Translations

12 source translations are retained for this English entry.

  • Arabic: مَادَّة سَوْدَاء — brain structure
  • Chinese Mandarin: 黑質 /黑质 (hēizhì) — brain structure
  • Finnish: mustatumake — brain structure
  • French: substantia nigra — brain structure
  • German: Substantia nigra — brain structure
  • Greek: μέλαινα ουσία (mélaina ousía) — brain structure
  • Japanese: 黒質 (kokushitsu) — brain structure
  • Latin: substantia nigra — brain structure
  • Polish: istota czarna — brain structure
  • Russian: чёрная субста́нция (čórnaja substáncija) — brain structure
  • Turkish: siyah madde — brain structure
  • Turkish: kara madde — brain structure