Standard Lemma guide

thrombospondin

noun · 1 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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  • Received-Pronunciation: /ˌθɹɒm.bə(ʊ)ˈspɒn.dɪn/
  • General-American: /ˌθɹɑm.boʊˈspɑn.dɪn/

1

noun

Meaning 1

Any of a family of glycoproteins secreted into the extracellular matrix by various types of cell, which play a role in cellular adhesion in processes including thrombocyte aggregation, tumor metastasis, and angiogenesis.

Definition source: English Wiktionary via Wiktextract

Usage: countable, uncountable

Topics: biochemistry, biology, chemistry, microbiology, natural-sciences, physical-sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

History

Etymology

From thrombin + respond + -in, coined in a 1972 paper by Baenziger et al., named due to its sensitivity to thrombin.https://web.archive.org/web/20060223143336/http://www.jbc.org/cgi/content/abstract/247/9/2723