Standard Lemma guide

variolation

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

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1

noun

Meaning 1

The inoculation of a person with smallpox with the intention of inducing a mild form of the illness and subsequent immunity to the disease.

Definition source: English Wiktionary via Wiktextract

Usage: countable, historical, uncountable

Examples

  • Variolation is no longer used today. It was replaced by smallpox vaccination, a safer alternative, which in turn led to the development of vaccines against many other diseases.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

the obsolete process of inoculating a susceptible person with material taken from a vesicle of a person who has smallpox

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: variolization

Antonyms: none provided

Broader terms: inoculating, vaccinating

History

Etymology

Etymology tree English variola Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English variolation From variola + -ation.

Across languages

Translations

4 source translations are retained for this English entry.

  • French: variolisation — inoculation with smallpox virus
  • Italian: variolizzazione — inoculation with smallpox virus
  • Italian: vaiolizzazione — inoculation with smallpox virus
  • Persian: آبلهکوبی (âbele-kôbi) — inoculation with smallpox virus