Phrase guide

xeroderma pigmentosum

noun · 2 senses · updated from the 2026-07-25 local source snapshot

Definitions and examples are grouped by meaning. Pronunciation, history, word forms, translations, descendants, synonyms, antonyms, derived terms, and related words appear whenever the source provides them.

Sound

Pronunciation

Each Play button uses your device's default local English voice, or a natural local fallback. The selected voice name appears after playback. This is synthesized speech, not a source recording.

No pronunciation record was provided for this word.

1

noun

Meaning 1

A rare genetic disorder in which DNA damaged by ultraviolet light is not repaired and the skin becomes sensitive to such light, in which a skin cancer can subsequently develop.

Definition source: English Wiktionary via Wiktextract

Usage: uncountable

Topics: medicine, sciences

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

2

noun

Meaning 2

a rare genetic condition characterized by an eruption of exposed skin occurring in childhood and photosensitivity with severe sunburn; inherited as a recessive autosomal trait in which DNA repair processes are defective so they are more likely to chromosome breaks and cancers when exposed to ultraviolet light

Definition source: Princeton WordNet 3.0

No example sentence was provided for this meaning.

Meaning relationships

Synonyms: none provided

Antonyms: none provided

Broader terms: xeroderma, xerodermia

History

Etymology

From Ancient Greek ξηρός (xērós, “dry”) δέρμα (dérma, “skin”) and Latin pigmentōsus (“pigmented, stained”).